全文获取类型
收费全文 | 4852篇 |
免费 | 395篇 |
国内免费 | 127篇 |
专业分类
耳鼻咽喉 | 769篇 |
儿科学 | 36篇 |
妇产科学 | 29篇 |
基础医学 | 422篇 |
口腔科学 | 403篇 |
临床医学 | 295篇 |
内科学 | 362篇 |
皮肤病学 | 47篇 |
神经病学 | 461篇 |
特种医学 | 143篇 |
外国民族医学 | 1篇 |
外科学 | 720篇 |
综合类 | 603篇 |
预防医学 | 229篇 |
眼科学 | 47篇 |
药学 | 424篇 |
6篇 | |
中国医学 | 177篇 |
肿瘤学 | 200篇 |
出版年
2024年 | 3篇 |
2023年 | 63篇 |
2022年 | 126篇 |
2021年 | 164篇 |
2020年 | 151篇 |
2019年 | 170篇 |
2018年 | 150篇 |
2017年 | 190篇 |
2016年 | 187篇 |
2015年 | 194篇 |
2014年 | 336篇 |
2013年 | 366篇 |
2012年 | 290篇 |
2011年 | 319篇 |
2010年 | 282篇 |
2009年 | 263篇 |
2008年 | 255篇 |
2007年 | 231篇 |
2006年 | 227篇 |
2005年 | 179篇 |
2004年 | 171篇 |
2003年 | 148篇 |
2002年 | 120篇 |
2001年 | 90篇 |
2000年 | 101篇 |
1999年 | 72篇 |
1998年 | 78篇 |
1997年 | 59篇 |
1996年 | 64篇 |
1995年 | 36篇 |
1994年 | 37篇 |
1993年 | 33篇 |
1992年 | 30篇 |
1991年 | 15篇 |
1990年 | 15篇 |
1989年 | 12篇 |
1988年 | 18篇 |
1987年 | 17篇 |
1986年 | 16篇 |
1985年 | 20篇 |
1984年 | 14篇 |
1983年 | 8篇 |
1982年 | 6篇 |
1981年 | 13篇 |
1980年 | 11篇 |
1979年 | 9篇 |
1978年 | 6篇 |
1977年 | 2篇 |
1976年 | 3篇 |
1974年 | 2篇 |
排序方式: 共有5374条查询结果,搜索用时 141 毫秒
31.
32.
David MATO Hajime YOKOTA Seiichiro HIRONO Juan MARTINO Naokatsu SAEKI 《Neurologia medico-chirurgica》2015,55(1):71-76
The vidian canal (VC), a bony tunnel in which the vidian artery and nerve pass, has been widely known as an important landmark to identify the anterior genu of the petrous carotid artery (AGPCA) especially during lateral extended endoscopic endonasal approachs (LEEEAs). The objectives of this study in the Japanese population are to describe the radiological anatomic features and relationships between VC and its surrounding structures, and discuss the clinical implications. We studied 231 high-resolution computed tomography (CT) scans with a slice thickness of 0.5 mm. All the patients had known sellar or parasellar pathologies but without any involvement of VC. The following VC-related parameters were examined: its length, relationship to AGPCA, course from the pterygopalatine fossa to the carotid canal, its position relative to the medial pterygoid plate and pneumatization pattern of the sphenoid sinus. Mean length of VC is 14.6 mm. There is more tendency of straight-running VC compared to other populations. VC locates infero-lateral to AGPCA in all the cases. The protrusion of VC and the paraclival carotid artery to the sphenoid sinus, as well as well-pneumatization of the sinus is also observed more frequently in almost a half of the population. Surgeons who perform LEEEAs in Japanese patients must know these anatomical features. The characteristics particular to Japanese populations may facilitate better identification of VC and exposure to AGPCA intraoperatively. 相似文献
33.
Incidence and survival trends of lip,intra-oral cavity and tongue base cancers in south-east England
O Olaleye U Ekrikpo O Lyne J Wiseberg 《Annals of the Royal College of Surgeons of England》2015,97(3):229-234
Background
Oral cavity cancers are on the increase in the UK. Understanding site-specific epidemiological trends is important for cancer control measures.This study demonstrates the changing epidemiological trends in lip, intra-oral cavity and tongue base cancers in south-east England from 1987 to 2006.Aim: Methods
This was a retrospective study using anonymised data obtained from the Thames Cancer Registry (TCR) London. Data were analysed using SPSS v.17 and survival analyses with Kaplan-Meier and Cox regression. Age standardisation of the incidence rates was performed. It was conducted in south-east England, which has an average population of 12 million. The study analysed 9,318 cases (ICD-10 code C00–C06, C14). Kent Research Ethics Committee UK granted ethical approval.Results
Oral cancers were more common in men, with male: female ratio of 1.6:1. Tongue cancers had the highest frequency at 3,088 (33.1%).Incidence varied with each cancer type. Mean incidence (per 1,000,000) ranged from 2.3 (lip cancer) to 13.8 (tongue cancer). There has been a statistically significant increase in incidence for cancers of the tongue base, other parts of tongue, gum and palate (p<0.001).Median survival time varied by sub-site, with lip cancer having the best median survival time (11.09 years) compared with tongue base cancer (2.42 years). Survival analyses showed worse prognosis for men, older age at diagnosis, and presence of synchronous tumours (p<0.001).Conclusion
There is a rising incidence of tongue and tongue base, gum and palate cancers in south-east England with wide variability in survival. Oral cancer awareness and screening programmes should be encouraged. 相似文献34.
35.
36.
37.
Objectives The integral involvement of sinus and skull base surgeries in the field of otolaryngology makes the endonasal vasculature including the ethmoidal arteries important to consider. The anterior ethmoidal artery (AEA) and posterior ethmoidal artery (PEA) are well-known entities, yet the relatively recent notion of accessory or middle ethmoidal vessels complicates our understanding of this arterial system.
Study Design Radiographic study.
Methods Fifty computed tomographic angiographies were studied for the presence of accessory/middle ethmoidal arteries (MEAs). If contrasted arteries were not visualized reliably, foramina were accepted as evidence of arteries. The accessory arteries/foramina were then compared with the locations of the AEA and PEA.
Results A total of 19 of the 50 patient samples studied had evidence of a right, left, or bilateral middle ethmoidal vessels (38%). Overall, 26 arteries total were identified out of the 100 sides (26%). Unilateral middle arteries were more common than bilateral, and right sided were more common than left. There was no evidence of multiple MEAs on a given side.
Conclusion The endonasal surgeon must be cognizant of the possible presence of MEAs. These arteries should be considered when working in the medial orbit and anterior skull base region. 相似文献
38.
Matthew R. Naunheim Ahmad R. Sedaghat Derrick T. Lin Benjamin S. Bleier Eric H. Holbrook William T. Curry Stacey T. Gray 《Skull base》2015,76(5):390-396
Objectives To characterize the temporal distribution and resolution rate of postoperative complications from endoscopic skull base surgery.
Design Retrospective review of patients undergoing endoscopic resection of paranasal sinus or skull base neoplasm from 2007 to 2013.
Setting Massachusetts General Hospital/Massachusetts Eye and Ear Infirmary Cranial Base Center.
Participants Fifty-eight consecutive patients.
Main Outcome Measures Postoperative complications were categorized as cerebrospinal fluid (CSF) leak, pituitary, orbital, intracranial, or sinonasal. Complications were temporally categorized as “perioperative” (within 1 week), “early” (after 1 week and within 6 months), or “delayed” (after 6 months).
Results The most common perioperative complications were diabetes insipidus (19.0%), CSF leak (5.2%), and meningitis (5.2%), with resolution rates of 75%, 100%, and 100%, respectively. Overall, CSF leak occurred in 13.8% of patients and resolved in all cases. A total of 53.8% of all complications were evident within 1 week of surgery. Chronic rhinosinusitis was the most common delayed complication (3.4%). Hypopituitarism and delayed complications were less likely to resolve (p = 0.014 and p = 0.080, respectively).
Conclusions Monitoring of complications after endoscopic skull base surgery should focus on neurologic complications and CSF leak in the early postoperative period and development of chronic rhinosinusitis in the long term. Late-onset complications and hypopituitarism are less likely to resolve. 相似文献
39.
Christine Dinh Mikhaylo Szczupak Seo Moon Simon Angeli Adrien Eshraghi Fred F. Telischi 《Skull base》2015,76(4):278-280
Objectives To describe a technique for harvesting larger temporal bone specimens from human cadavers for the training of otolaryngology residents and fellows on the various approaches to the lateral and posterolateral skull base.
Design Human cadaveric anatomical study. The calvarium was excised 6 cm above the superior aspect of the ear canal. The brain and cerebellum were carefully removed, and the cranial nerves were cut sharply. Two bony cuts were performed, one in the midsagittal plane and the other in the coronal plane at the level of the optic foramen.
Setting Medical school anatomy laboratory.
Participants Human cadavers.
Main Outcome Measures Anatomical contents of specimens and technical effort required.
Results Larger temporal bone specimens containing portions of the parietal, occipital, and sphenoidal bones were consistently obtained using this technique of two bone cuts. All specimens were inspected and contained pertinent surface and skull base landmarks.
Conclusions The skull base block method allows for larger temporal bone specimens using a two bone cut technique that is efficient and reproducible. These specimens have the necessary anatomical bony landmarks for studying the complexity, utility, and limitations of lateral and posterolateral approaches to the skull base, important for the education of otolaryngology residents and fellows. 相似文献
40.
Marco A. Mascarella Reza Forghani Salvatore Di Maio Denis Sirhan Anthony Zeitouni Gerard Mohr Marc A. Tewfik 《Skull base》2015,76(3):195-201
Objective To identify clinicopathologic factors associated with a reduced intercarotid distance (ICD) and subgroups at risk for internal carotid artery injury during transsphenoidal surgery.
Design A retrospective case-control study.
Setting This study was conducted at the McGill University Health Centre, a university-affiliated tertiary care center.
Participants Patients with a sellar or parasellar tumor and nontumor controls were included in the study.
Main Outcome Measures The smallest distance between the internal carotid arteries at the clival, cavernous, and paraclinoid segments on coronal magnetic resonance imaging was measured. Demographic profiles, cephalometric measurements, tumor dimensions, and sphenoid configuration were assessed as potential determinants of the ICD.
Results A total of 212 cases and 34 controls were analyzed. Widening of the ICD at the three segments of the internal carotid arteries was found in patients with pituitary macroadenomas (p < 0.01). Patients with a growth hormone–secreting adenoma had a markedly reduced ICD at the clivus compared with controls (1.59 cm versus 1.77 cm; p = 0.02; 95% confidence interval [CI], 0.03–0.32). The paraclinoid ICD was reduced in patients with an anterior fossa meningioma (1.24 cm versus 1.33 cm; p = 0.04; 95% CI, 0.01–0.45).
Conclusion Identifying clinicopathologic factors affecting the ICD can help surgeons recognize constraints to endoscopic access of the skull base and avoid inadvertent arterial injury. 相似文献